A Case of Triple-negative Breast Cancer with Squamous Metaplasia in which a Pathologic Complete Response was Achieved with Neoadjuvant Chemotherapy
نویسندگان
چکیده
منابع مشابه
Relationship between Complete Pathologic Response to Neoadjuvant Chemotherapy and Survival in Triple-Negative Breast Cancer.
PURPOSE Pathologic complete response (pCR) to neoadjuvant chemotherapy reflects the cytotoxic efficacy of a drug, but patient survival is influenced by many other factors. The purpose of this study was to assess the relationship between increased pCR rate and trial-level survival benefit in triple-negative breast cancer (TNBC). EXPERIMENTAL DESIGN We used bootstrap resampling from a neoadjuva...
متن کاملPathologic response after neoadjuvant chemotherapy predicts locoregional control in patients with triple negative breast cancer
PURPOSE Our goal was to determine the impact of pathologic response after neoadjuvant chemotherapy in triple negative breast cancer (TNBC) on the subsequent risk of locoregional recurrence (LRR) and disease-free survival (DFS) in the setting of adjuvant radiation therapy. METHODS AND MATERIALS This was an institutional review board-approved retrospective chart review of patients with clinical...
متن کاملImpact of weight change during neoadjuvant chemotherapy on pathologic response in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is an uncommon but aggressive subtype of breast cancer. Obesity has been associated with an increased risk of breast cancer and worse prognosis. Some studies suggest that obese patients are less likely to achieve pathologic complete response (pCR) to neoadjuvant chemotherapy (NCT) and experience worse overall survival. Ki-67 is a proliferation marker that co...
متن کاملCancer Therapy: Clinical Relationship between Complete Pathologic Response to Neoadjuvant Chemotherapy and Survival in Triple-Negative Breast Cancer
Purpose: Pathologic complete response (pCR) to neoadjuvant chemotherapy reflects the cytotoxic efficacy of a drug, but patient survival is influenced by many other factors. The purpose of this studywas to assess the relationshipbetween increasedpCR rate and trial-level survival benefit in triple-negative breast cancer (TNBC). Experimental Design:We used bootstrap resampling from a neoadjuvant t...
متن کاملPredictive ability of 18F-fluorodeoxyglucose positron emission tomography/computed tomography for pathological complete response and prognosis after neoadjuvant chemotherapy in triple-negative breast cancer patients
Objective The mortality of patients with locally advanced triple-negative breast cancer (TNBC) is high, and pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) is associated with improved prognosis. This retrospective study was designed and powered to investigate the ability of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) to predict pat...
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ژورنال
عنوان ژورنال: Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
سال: 2015
ISSN: 1345-2843,1882-5133
DOI: 10.3919/jjsa.76.478